diff --git a/Vue/Pharmacien/index.php b/Vue/Pharmacien/index.php
index 5be2ed2..0e2ff9c 100755
--- a/Vue/Pharmacien/index.php
+++ b/Vue/Pharmacien/index.php
@@ -318,7 +318,7 @@
 				<table class="table table-striped table-hover table-bordered table-condensed table-responsive" style='font-size:9pt;'>
 					<thead>
 					  <tr>
-						<th style="text-align:center"> <?= _("Subtitut") ?> </th>
+						<th colspan='2' style="text-align:center"> <?= _("Subtitut") ?> </th>
 						<th style="text-align:center"> <?= _("Nom") ?> </th>
 						<th style="text-align:center"> <?= _("Forme") ?>  </th>
 						<th style="text-align:center"> <?= _("Prix Unitaire") ?>  </th>
@@ -379,9 +379,14 @@
 					?>
 						<tr valign="top">
 							<?php if($livre == "0") : ?>
-								<td width="5%" align='center'> <input type="button" value=" ... " onClick="javascript:substituer_medicament('<?= $idMedicament ?>','<?= $posologie ?>', '<?= $idDemandeSubstitution ?>','<?= $quantite ?>','<?= $codeMedicamentSubstitut ?>','<?= $idDetail ?>');"></td>
+								<?php if($codeMedicamentSubstitut>""): ?>								
+									<td width="5%" align='center'> <input type="button" value=" ... " onClick="javascript:substituer_medicament('<?= $idMedicament ?>','<?= $posologie ?>', '<?= $idDemandeSubstitution ?>','<?= $quantite ?>','<?= $codeMedicamentSubstitut ?>','<?= $idDetail ?>');"></td>
+									<td width="5%" align='center'> <input type="button" value=" .-. " onClick="javascript:annuler_substit_medicament('<?= $idDetail ?>');"></td>
+								<?php else: ?>
+									<td width="10%" align='center'> <input type="button" value=" ... " onClick="javascript:substituer_medicament('<?= $idMedicament ?>','<?= $posologie ?>', '<?= $idDemandeSubstitution ?>','<?= $quantite ?>','<?= $codeMedicamentSubstitut ?>','<?= $idDetail ?>');"></td>
+								<?php endif; ?>
 							<?php else: ?>
-								<td width="5%" align='center'>S</td>
+								<td width="10%" align='center'>S</td>
 							<?php endif; ?>
 							<?php if($substituable=="1") : ?>
 								<td align='center' style="background-color: yellow;">  <?= $libelleMedicament . " => " .  $nomSubstitut ?> </td>